Developmental biology
PRINCIPAL INVESTIGATOR
Julio T. Ávila Marrero
Professor of Biochemistry and Molecular Biology, Department of Biochemistry, Microbiology, Cellular Biology and Genetics, ULL |
Pablo Martín Vasallo
Professor of Biochemistry and Molecular Biology, Department of Biochemistry, Microbiology, Cellular Biology and Genetics, ULL |
EXTERNAL COLLABORATORS:
- Manuel José Morales González (Associate Lecturer in Internal Medicine, Head of the Medical Oncology Service, HUNSC)
- Ángela Palumbo (Medical Director, In vitro Fertilization Centre)
- Jairo Hernández Hernández (Laboratory Director, In vitro Fertilization Centre)
- Deborah Rotoli (Visiting Investigator)
- Rebeca González Fernández (SEGAI technician, ULL)
PHD STUDENTS AND TRAINEES:
- Rita Marleny Martín Ramírez (PhD student, The Canary Islands Agency of Research, Innovation and Information Sciences, ACIISI)
- Fabián Leopoldo Poletti Serafini (Traumatology service H. San Juan de Dios, Doctorate Program in Health Sciences)
- María Adela Rodríguez Fuentes (Radiology Service HUC, Doctorate Program in Health Sciences)
- Miriam Dorta Suárez (Medical Oncology-HUNSC)
RESEARCH LINES:
- Gene expression in granulose and cumulus cells during follicular ovarian cancer development in humans.
- Study of the changes in gene expression associated with the administration of chemotherapy to cancer patients.
- Molecular Biology and the cellular Na+/K+-ATPase
PUBLICATIONS 2019:
- Rotoli D,Morales M,Maeso MD,Ávila J,Pérez-Rodríguez ND,Mobasheri A,vanNoorden CJF,Martín-Vasallo P. IQGAP1, AmotL2, and FKBP51 Scaffoldins in the Glioblastoma Microenvironment. J Histochem Cytochem. 2019 Jul;67(7):481-494. doi: 10.1369/0022155419833334
- Mobasheri A, Matta C, Uzielienè I, Budd E, Martín-Vasallo P, Bernotiene E. The chondrocyte “channelome”: A narrative review. [Le «channelome» du chondrocyte. Revue narrative]. Revue du Rhumatisme (Edition Francaise). 2019 Mar;86(2):147-154. doi: 10.1016/j.rhum.2018.08.001
- Mobasheri A,Matta C,Uzielienè I,Budd E, Martín-Vasallo P,Bernotiene E. The chondrocyte channelome: A narrative review. Joint Bone Spine. 2019 Jan;86(1):29-35. doi: 10.1016/j.jbspin.2018.01.012
OTHER SELECTED PUBLICATIONS FROM THE LAST 10 YEARS:
- Rotoli D, Morales M, Del Carmen Maeso M, Del Pino Garcia M, Morales A, Avila J, Martin-Vasallo P. Expression and localization of the immunophilin FKBP51 in colorectal carcinomas and primary metastases, and alterations following oxaliplatin chemotherapy. Oncol Lett. 2016 Aug;12(2):1351-1322. doi: 3892/ol.2016.4772
- Baker Bechmann M, Rotoli D, Morales M, Maeso M del C, Garcia M, Ávila J, Mobasheri A, Martín-Vasallo P. Na,K-ATPase Isozymes in Colorectal Cancer and Liver Metastases. Front Physiol. 2016 Jan 29;7:9. doi: 10.3389/fphys.2016.00009
- González-Fernández R, Ávila J, Arteaga MF, Canessa CM, Martín-Vasallo P. The neuronal-specific SGK1.1 (SGK1_v2) kinase as a transcriptional modulator of BAG4, Brox, and PPP1CB genes expression. Int J Mol. Sci. 2015 Apr 2;16(4):7462-77. doi:10.3390/ijms16047462
- González-Fernández R, Morales M, Avila J, Martín-Vasallo P. Changes in leukocyte gene expression profiles induced by antineoplastic chemotherapy. Oncol Lett. 2012Jun; 3(6):1341-1349. doi: 3892/ol.2012.669
- Mobasheri A, Trujillo E, Arteaga MF, Martín-Vasallo P. Na(+), K(+)-ATPase Subunit Composition in a Human Chondrocyte Cell Line; evidence for the Presence of A1, A3, B1, B2 and B3 Isoforms. Int J Mol Sci. 2012;13(4):5019-34. doi: 10.3390/ijms13045019